Stop taking clomiphene and seek emergency medical attention if you experience an allergic reaction (such as difficulty breathing, closing of your throat, swelling of your lips, tongue, or throat).

The ovarian hyperstimulation syndrome (OHSS) has been reported to occur in patients receiving clomiphene. Symptoms of OHSS include swelling of the hands or legs, abdominal pain and swelling, shortness of breath, weight gain, and nausea or vomiting. OHSS can be fatal. Please notify your doctor immediately or seek emergency medical attention if you develop any of these side effects.

Other side effects may also occur. Notify your doctor if you experience:

ovarian enlargement presenting as abdominal or pelvic pain, tenderness, pressure, or swelling
flushing
nausea, vomiting, or diarrhea
breast tenderness or discomfort
blurred vision or other visual disturbances
headache
abnormal uterine bleeding

Note: Clomiphene may increase the likelihood of multiple births. Multiple births may carry additional risk both for the mother and for the fetuses.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

 

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